Idebenone CAS 58186-27-9 for Treat Central Nervous System Disease Food/Cosmetics Grade

• CAS No.: 58186-27-9
• Formula: C19h30o5
• EINECS: 1308068-626-2
• Environmental Protection: Yes
• Certification: REACH
• Color: Yellow
• Model NO.: 98%
• Classification: Coenzyme
• Function: Nourishing and Balancing Nutrition
• Appearance: Powder
• Transport Package: 1kg-25kgs
• Specification: 98%
• Trademark: SunhealthBio
• Origin: China
• Production Capacity: 1000t/Year

Product Description

Description

Melting point	52-550C
Boiling point	497.3±45.0 °C(Predicted)
density	1.08±0.1 g/cm3(Predicted)
storage temp.	room temp
solubility	Soluble in DMSO (up to 25 mg/ml).
form	neat
pka	15.20±0.10(Predicted)
color	Orange

Function

Idebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects.Target: OthersIdebenone is a synthetic variant of coenzyme Q10 (CoQ10), which initially developed for the treatment of Alzheimer's disease and other cognitive defects. Idebenone was generally well tolerated with similar numbers of adverse events in each group. One child receiving high-dose idebenone developed neutropenia after 6 months, which resolved after discontinuation of treatment. 8OH2′dG concentrations were not increased, and did not significantly change with idebenone treatment [1]. The 2-year efficacy and safety of idebenone were studied in a prospective, randomized, double-blind multicentre study in 3 parallel groups of patients with dementia of the Alzheimer type (DAT) of mild to moderate degree. A total of 450 patients were randomized to either placebo for 12 months, followed by idebenone 90 mg tid for another 12 months (n = 153) or idebenone 90 mg tid for 24 months (n = 148) or 120 mg tid for 24 months (n = 149). idebenone showed statistically significant dose-dependent improvement in the primary efficacy variable ADAS-Total and in all the secondary efficacy variables [2].

Application

Cosmetics grade:
Idebenone is a highly lipophilic compound that can also be heated and dissolved with appropriate amounts of grapeseed oil. It's structurally similar to coenzyme Q10. As a highly effective antioxidant, it has the functions of scavenging free radicals, inhibiting lipid peroxidation, inhibiting inflammation, inhibiting DNA damage, light protection, reducing pigmentation, improving fine lines, wrinkles and age spots and other cosmetics.
Food grade:
Idebenone Used as cerebral circulation improving medicine, intelligence promoting medicine.
Idebenone is a powerful antioxidant and positively affects brain chemistry.
Idebenone has been shown to promote information transfer across the corpus callosum, the membrane separating the right and left brain hemispheres.
Idebenone has been used to treat Alzheimer's and to lessen damage from strokes.
Idebenone can increase production of the brain neurotransmitters serotonin, dopamine, adrenalin, and noradrenanlin.

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FAQ

 

Q1. What's your payment terms?
T/T  L/C  Paypal  Western Union.

Q2. What's your delivery time?
Usually we will arrange the shipment in 7 -15 days,due to different products you choose.

Q3. How about the packing?
Usually we provide the packing as 25 kg / bag or carton,and also as your request bag.

Q4. How about the validity of the products?
According to the products you ordered.

Q5. What documents you provide?
Usually, we provide Commerical Invoice, Packing List, Bill of loading, COA ,Origin certificate. 

If your markets have any special requirements, let us know.

Q6. What is loading port?
Usually is Shanghai,Beijing or Shenzhen.

Q7:Can we have samples for development?
We can provide free samples (small quantity) to you, but the freight cost on buyer's account.
Q8: Can you do customized?
We can make the products as per customers' requested products and quantity